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BIOGRAPHICAL SKETCH
David N. Levin received his Ph.D. in theoretical physics from Harvard University in 1970 and did research in quantum field theory until 1977, when he entered medical school at the University of Chicago. He joined the faculty after receiving an MD and completing radiology residency at the University. From 1987-1999, he served as Director of Clinical MRI at the University and from 1999-2005 he co-directed the University's Brain Research Imaging Center. He is currently professor in the Department of Radiology.
His past research interests have included multimodality 3D brain imaging, computer-assisted neurosurgery, and image segmentation. His current research is focused on the development of new methodology for mapping the brain with functional MRI and for using prior knowledge to increase the speed of MR image acquisition.
SELECTED PUBLICATIONS
Papers in Molecular Biology:
1. Folsome CE and Levin DN. Detecting reversion in T4rII bacteriophage to r+ induced by ultra-violet irradiation. Nature 1961; 192:1306.
Papers in Theoretical Physics
2. Levin DN. Off-mass-shell corrections to current-algebra calculations of pi-nucleon S-wave scattering lengths. Physical Review 1968; 174:1759-1763.
3. Levin DN. Current algebra, pi-pi scattering lengths, and the rho leptonic-decay branching ratio. Physical Review 1969; 181:2083-2087.
4. Levin DN. Formal restrictions on Schwinger terms in commutators containing J and/or theta. Physical Review 1971; D3:1320-1326.
5. Levin DN, Palmer DR. The dimensions of scale-invariance-breaking and the behavior of the pion’s mechanical form factor Physical Review 1971; D4:3716-3725.
6. Levin DN, Okubo S, Palmer DR. The dimension of scale-invariance-breaking interactions. Physical Review 1971; D4:1847-1850.
7. Levin DN, Mathur VS, Okubo S. Bounds on the pion’s charge radius. Physical Review 1972; D5:912-915.
8. Levin DN, Okubo S. Can the pion’s charge radius be large? Physical Review 1972; D6:3149-3161.
9. Levin DN, Okubo S. Implications of a large pionic charge radius. Physics Letters 1972; 42B:233-235.
10. Cornwall JM, Levin DN, Tiktopoulos G. Uniqueness of spontaneously-broken gauge theories. Physical Review Letters 1973; 30:1268-1270.
11. Cornwall JM, Levin DN, Tiktopoulos G. A new class of renormalizable vector-meson theories? Physical Review Letters 1974; 32:498-501.
12. Cornwall JM, Levin DN, Tiktopoulos G. Derivation of gauge-invariance from high-energy unitarity bounds on the S-matrix. Physical Review 1974; D10:1145-1167.
13. Levin DN, Tiktopoulos G. Search for all renormalizable interactions. Physical Review 1975; D12:415-419.
14. Levin DN. Renormalizable interactions with only one coupling constant. Physical Review 1976; D13:832-837.
15. Levin DN. High energy behavior of field strength interactions. Physical Review 1976; D14:465-471.
16. Levin DN. Semisimple unified gauge theories of strong, weak, and electromagnetic interactions. Physical Review 1978; D17:2695-2712.
Papers in Electrophysiology:
17. Levin DN. Surface capacity of electrically syncytial tissues. Biophys J 1981; 35:127-146.
18. Levin DN. Unit membrane parameters of electrically syncytial tissues. Biophys J 1981; 35:147-165.
19. Levin DN and Fozzard HA. A cleft model for cardiac Purkinje strands. Biophys J 1981; 33:383-408.
Papers in Magnetic Resonance:
20. Lauterbur PC, Levin DN, Marr RB. Theory and simulation of NMR spectroscopic imaging and field plotting by projection reconstruction involving an intrinsic frequency dimension. J Mag Res 1984; 59:536-541.
21. Stillman AE, Levin DN, Yang DB, Marr RB, Lauterbur PC. Back projection reconstruction of spectroscopic NMR images from incomplete sets of projections. J Mag Res 1986; 69:168-175.
22. Levin DN, Herrmann A, Spraggins T, Collins PA, Dixon LB, Simon MA, Stillman AE. Musculoskeletal tumors: improved depiction with linear combinations of MR images. Radiology 1987; 163:545-549.
23. Herrmann A, Levin DN, Beck RN. Oscillating intensity display of soft tissue lesions in MRI. IEEE: Trans Med Imag 1987; MI-6:370-373.
24. Liebman CE, Messersmith RN, Levin DN, Lu C-T. MR imaging of inferior vena caval filters: safety and artifacts. Am J Roentgen 1988; 150:1174-1176.
25. Hu X, Levin DN, Lauterbur PC, Spraggins T. SLIM: spectral localization by imaging. Magnetic Resonance in Medicine 1988; 8:314-322.
26. Levin DN, Pelizzari CA, Chen GTY, Chen C-T, and Cooper MD. Retrospective geometric correlation of MR, CT and PET images. Radiology 1988; 169:817-823.
27. Levin DN, Hu X, Tan KK, and Galhotra S. Surface of the brain: three-dimensional MR images created with volume-rendering. Radiol 1989; 171:277-280.
28. Levin DN, Hu X, Tan KK, Galhotra S, Pelizzari CA, Chen GTY, Beck RN, Chen CT, Cooper MD, Mullan JF, Hekmatpanah J, and Spire JP. The brain: integrated three-dimensional display of MR and PET images. Radiol 1989; 172:783-789.
29. Hu X, Tan KK, Levin DN, Galhotra S, Mullan JF, Hekmatpanah J, and Spire JP. Three-dimensional magnetic resonance images of the brain: application to neurosurgical planning. J Neurosurg 1990; 72:433-440.
30. Hu X, Alperin N, Levin DN, Tan KK, Mengeot M. Visualization of MR angiographic data with segmentation and volume-rendering techniques. J Mag Reson Imag 1991; 1:539-546.
31. Fishman EK, Magid D, Ney DR, Chaney EL, Pizer SM, Rosenman JG, Levin DN, Vannier MW, Kuhlman JE, Robertson DD. State of the art: three-dimensional imaging. Radiol 1991; 181:321-337.
32. Grzeszczuk R, Tan KK, Levin DN, Pelizzari CA, Hu X, Chen GTY, Beck RN, Chen C-T, Cooper M, Milton J, Spire J-P, Towle VL, Dohrmann GJ, and Erickson RK. Retrospective fusion of radiographic and MR data for localization of subdural electrodes. J Comput Assist Tomogr 1992; 16:764-773.
33. Cao Y and Levin DN. MR imaging with spatially variable resolution. J Mag Reson Imag 1992; 2:701-709.
34. Towle VL, Bolanos J, Suarez D, Tan K, Grzeszczuk R, Levin DN, Cakmur R, Frank S, and Spire J-P. The spatial location of EEG electrodes: locating the best-fitting sphere relative to cortical anatomy. Electroencephalography and Clinical Neurophysiology 1993; 86:1-6.
35. Tan KK, Grzeszczuk R, Levin DN, Pelizzari CA, Chen GTY, Erickson RK, Johnson D, and Dohrmann GJ. A frameless stereotactic approach to neurosurgical planning based on retrospective patient-image registration. J Neurosurg 1993; 79:296-303.
36. Cao Y, Towle VL, Levin DN, and Balter JM. Functional mapping of human motor cortical activation by conventional MRI at 1.5 T. J Mag Reson Imag 1993; 3:869-875.
37. Cao Y and Levin DN. Feature-recognizing MRI. Mag Reson in Med 1993; 30:305-317.
38. Cao Y, Levin DN, Gregory CD, Raidy T, So GJ, and Pelizzari CA. Integrated 3-D display of brain surface anatomy and MR spectral data. Mag Reson Imag 1993; 11:1043-1049.
39. Alperin N, Levin DN, and Pelizzari CA. Retrospective registration of x-ray angiograms with MR images by using vessels as intrinsic landmarks. J Mag Reson Imag 1994; 4:139-144.
40. Cao Y, Vikingstad EM, Huttenlocher PR, Towle VL, and Levin DN. Functional magnetic resonance studies of the reorganization of the human hand sensorimotor area after unilateral brain injury in the perinatal period. Proc Nat'l Acad Sci 1994; 91:9612-9616.
41. Cao Y and Levin DN. Using an image database to constrain the acquisition and reconstruction of MR images of the human head. IEEE Trans Med Imaging 1995; 14: 350-361.
42. Cao Y and Levin DN. On the relationship between feature-recognizing MRI and MRI encoded by singular value decomposition. Magn Reson Med 1995; 33:140-142.
43. Cao Y, Levin DN, and Yao L. Locally focused MRI. Magn Reson Med 1995; 34:858-867.
44. Cao Y and Levin DN. Acquisition and reconstruction of the principal components of an image: a novel MRI technique for reducing scanning time. Internat J of Imaging Systems and Technol. 1995; 6:191-202.
45. Yao L, Cao Y, and Levin DN. 2D locally focused MRI: applications to dynamic and spectroscopic imaging. Magn. Reson. Med. 1996; 36:834-846.
46. Alperin N, Vikingstad EM, Gomez-Anson B, and Levin DN. Hemodynamically-independent analysis of CSF and brain motion observed with dynamic phase-contrast MRI. Magn Reson Med 1996; 35:741-754.
47. Ryan MJ, Erickson RK, Levin DN, Pelizzari CA, Macdonald RL, and Dohrmann GJ. Frameless stereotaxy with real-time tracking of patient head movement and retrospective patient-image registration. J. Neurosurgery 1996; 85:287-292.
48. Cao Y and Levin DN. Using prior knowledge of human anatomy to constrain MR image acquisition and reconstruction: half k-space and full k-space techniques. Magn. Reson. Imaging 1997; 15:669-677.
49. Grzeszczuk RP and Levin DN. "Brownian strings": segmenting images with stochastically deformable contours. IEEE Trans. Pattern Analysis Machine Intellig. 1997; 19:1100-1114.
50. Kuperman VY, Nagle SK, and Levin DN. Locally focused MRI of interventions. J. Magn. Reson. Imaging 1998; 8:1288-1295.
51. Chu D, Levin DN, and Alperin N. Assessment of the biomechanical state of intracranial tissues by dynamic MRI of cerebrospinal fluid pulsations: a phantom study. Magn. Reson. Imaging 1998; 16:1043-1048.
52. Nagle SK and Levin DN. Multiple region MRI. Magn. Reson. Med. 1999; 41:774-786.
53. Kuperman VY, Nagle SK, Alley MT, Glover GH, and Levin DN. Locally-focused contrast-enhanced carotid MRA. J. Magn. Reson. Imaging 1999; 9:663-669.
54. Chu D, Huttenlocher PR, Levin DN, and Towle VL. Reorganization of hand somatosensory cortex following perinatal unilateral brain injury. Neuropediatrics, April 2000;31: 63-69.
55. Uftring SJ. Chu D. Alperin N. and Levin DN. The mechanical state of intracranial tissues in elderly subjects studied by imaging CSF and brain pulsations. Magn. Reson. Imaging 2000: 18:991-996.
56. Levin DN and Uftring SJ. Detecting brain activation in fMRI data without prior knowledge of mental event timing. NeuroImage 2001: 13: 153-160.
57. Uftring SJ. Wachtel SR. Chu D. McCandless C. Levin DN. and de Wit H. An fMRI study of the effect of amphetamine on brain activity.
Neuropsychopharmacology 2001; 25: 925-935.
58. Nagle SK. and Levin DN. Creating a library of generalized Fourier sampling patterns for irregular 2D regions of support. Magn. Reson. Med. 2001; 46: 624-627.
Papers in Signal Processing:
59. Levin DN. A differential geometric description of the relationships among perceptions. J. Math. Psych. 2000; 44: 241-284.
60. Levin DN. Representations of sound that are insensitive to spectral filtering and parameterization procedures. J. Acoust. Soc. Am. 2002; 111: 2257-2271.
61. Levin DN. Sensor-independent stimulus representations. Proc. Nat. Acad. Sci. 2002; 99: 7346-7351.
62. Levin DN. Blind normalization of speech from different channels. J. Acoust. Soc. Am. 2004; 116: 519-529.
63. Levin DN. Channel-independent and sensor-independent stimulus representations. J. Applied Physics 2005; 98: 104701.
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