INTRODUCTION
Maryellen L. Giger
Vice Chair for Basic Science Research
Michael Vannier
Vice Chair for Clinical Science Research
The Department of Radiology has 14 basic science faculty members
with imaging science research interests including evaluation
methodologies & ROC analysis, computer-aided diagnosis &
computerized image analysis for the interpretation of a variety of
medical images (such as breast, thoracic, colon, cardiac, skeletal &
radioisotope images), new acquisition methods for MRI and MRIS,
novel tomographic reconstruction methods, new methods for PET, SPECT
and optical imaging, and developments of novel imaging
instrumentation. The faculty labs include over seventy
grant-supported researchers including research lab computer
scientists & staff, research associates (assistant professors),
post-docs, graduate students, medical students, undergraduates, and
high school students.
The worldfs first use of Tc-99m for medical imaging was
demonstrated at the UC. Theoretical and application developments for
physical image quality assessment of spatial resolution, noise, and
contrast were investigated for both analog and digital imaging
systems. Research & developments in medical decision making & ROC
analysis have benefited researchers around the world through the
free availability of state-of-the-art ROC analysis software. Image
co-registration and integration research done at UC in the 1980s
germinated the field of multi-modality imaging. University of
Chicago pioneered the field of computer-aided diagnosis, developing
the first prototype for mammographic CAD in the early 1990fs.
Ground-breaking developments in tomographic image reconstruction
have been made yielding analytic solutions to the complex 3D and 4D
problems. More recently, developments in small-animal MRI have lead
to the first image of mammary DCIS in a mouse model. In addition,
research at the UC includes solving important problems in muscle and
cardiovascular physiology such as NMR detection of gene expression..
Exciting research highlights of the faculty can be seen through
this website.
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